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Invitrogen™ SLC19A1 Polyclonal Antibody
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Catalog No. PIPA588778
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100 μL
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PIPA588778 100 μL
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Catalog No. PIPA588778 Supplier Invitrogen™ Supplier No. PA588778
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: LDGLRHCQRG HHPRQPPAQG LRSAAEEKAA QALSVQDKGL GGLQPAQSPP LSPEDSLGAV GPASLEQRQS DPYLAQAPAP QAAEFLSPVT TPSPCTLCSA QASGPEAADE TCPQLAVHPP GVSKLGLQCL PSDGVQNVNQ; Positive Samples: HeLa, U-87MG; Cellular Location: Membrane, Multi-pass membrane protein.

Transport of folate compounds into mammalian cells can occur via receptor-mediated or carrier-mediated mechanisms. A functional coordination between these 2 mechanisms has been proposed to be the method of folate uptake in certain cell types. Methotrexate (MTX) is an antifolate chemotherapeutic agent that is actively transported by the carrier-mediated uptake system. RFC1 plays a role in maintaining intracellular concentrations of folate.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SLC19A1
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.19 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene SLC19A1
Gene Accession No. P41440
Gene Alias AI323572; CHMD; FLOT1; folate transporter 1; FOLT; IFC1; IFC-1; Intestinal folate carrier 1; intestinal folate carrier protein; methotrexate carrier 1; methotrexate carrier 2; methotrexate carrier 5; methotrexate carrier 6; MTX1; MTX-1; Placental folate transporter; reduced folate carrier 1; Reduced folate carrier protein; Reduced folate transporter; Reduced folate transporter 1; REFC; RFC; RFC1; RFC-1; RFT-1; SLC19A1; solute carrier family 19 (folate transporter), member 1; solute carrier family 19 (sodium/hydrogen exchanger), member 1; solute carrier family 19 member 1; solute carrier family 19, member 1
Gene Symbols SLC19A1
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 452-591 of human SLC19A1 (NP_9192311).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6573
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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