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Invitrogen™ SLC1A6 Polyclonal Antibody
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Catalog No. PIPA559600
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100 μL
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PIPA559600 100 μL
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Catalog No. PIPA559600 Supplier Invitrogen™ Supplier No. PA559600
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: KQFKTQYSTR VVTRTMVRTE NGSEPGASMP PPFSVENGTS FLENVTRALG TLQEMLSFEE TVPVPGS Highest antigen sequence identity to the following orthologs: Mouse - 85%, Rat - 82%.

Slc1a6 encodes a protein that is a glutamate transporters, also known as excitatory amino acid transporters (EAATs), are sodium- and potassium-dependent members of the solute carrier family 6 (SLC1), widely distributed throughout the brain. There are five EAAT subtypes, each with a specific distribution. Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate. Slc1a6 functions as a symporter that transports one amino acid molecule together with two or three Na(+) ions and one proton, in parallel with the counter-transport of one K(+) ion. Slc1a6 also mediates Cl(-) flux that is not coupled to amino acid transport and this avoids the accumulation of negative charges due to aspartate and Na(+) symport. Further, Slc1a6 [lays a redundant role in the rapid removal of released glutamate from the synaptic cleft, which is essential for terminating the postsynaptic action of glutamate (Probable). Diseases associated with SLC1A6 include Dicarboxylic Aminoaciduria.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SLC1A6
Applications Immunohistochemistry (Paraffin), Immunocytochemistry
Classification Polyclonal
Concentration 0.9 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene SLC1A6
Gene Accession No. P48664
Gene Alias EAAT4; Excitatory amino acid transporter 4; high affinity aspartate/glutamate transporter; high-affinity neuronal glutamate transporter; Slc1a6; Sodium-dependent glutamate/aspartate transporter; solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6; solute carrier family 1 member 6; solute carrier family 1, member 6
Gene Symbols SLC1A6
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human SLC1A6. Recombinant protein control fragment (Product #RP-98970).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6511
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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