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Invitrogen™ SLC22A2 Polyclonal Antibody
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Catalog No. PIPA589602
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100 μL
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PIPA589602 100 μL
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Catalog No. PIPA589602 Supplier Invitrogen™ Supplier No. PA589602
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: GFTPDHRCRS PGVAELSLRC GWSPAEELNY TVPGPGPAGE ASPRQCRRYE VDWNQSTFDC VDPLASLDTN RSRLPLGPCR DGWVYETPGS SIVTEFN; Positive Samples: Mouse kidney; Cellular Location: Membrane, Multi-pass membrane protein.

Organic cation transporters (OCT) are expressed in the plasma membrane of epithelial cells from a wide range of tissues, where they function in the elimination of endogenous amines, cationic drugs and other xenobiotics. The structure of OCTs consists of a 12-transmembrane-domain structure and a large extracellular hydrophilic loop. In humans, OCT1 is primarily expressed in the liver, while OCT2 is expressed in the kidney. OCT3 is expressed in the placenta, skeletal muscle, prostate, aorta and liver. OCT2, also known as SLC22A2, is a multi-specific transporter protein localizing to the basolateral and luminal membranes of the kidney distal tubule and proximal tubules. OCT2 is responsible for mediating the pH-sensitive tubular uptake of organic compounds from circulation. An additional splice variant exists for OCT2, namely OCT2-A.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SLC22A2
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 1.38 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Slc22a2
Gene Accession No. O70577
Gene Alias 2-Oct; hOCT2; OCT2; OCT2r; Orct2; Organic cation transporter 2; rOCT2; Slc22a2; solute carrier family 22 (organic cation transporter), member 2; solute carrier family 22 member 2; solute carrier family 22, member 2
Gene Symbols Slc22a2
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 44-140 of human SLC22A2 (NP_0030492).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 20518
Target Species Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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