Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

Invitrogen™ SLC22A5 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA580016

Catalog No. PIPA580016


Only null left
Add to Cart

Description

Description

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: Rat Kidney Tissue, Rat Skeletal Muscles Tissue, Mouse Liver Tissue, HEPA Cell, NIH3T3 Cell.

Carnitine (b-hydroxy-g-trimethylaminobutyrate) is a small, highly polar compound that aids in the b-oxidation of long-chain fatty acids. Organic cation/carnitine transporters (OCTN) assist in the elimination of cationic compounds, including xenobiotics, and transport carnitine for reabsorption in the kidney. Similar to organic cation transporters (OCT), OCTN proteins localize to the plasma membrane of epithelial cells. OCTN1 is expressed in kidney, trachea, bone marrow and fetal liver. OCTN2 is abundantly expressed in kidney, skeletal muscle, placenta and heart. OCTN3 is strongly expressed in testis and weakly expressed in kidney. The gene encoding human OCTN1 maps to chromosome 5 and the gene encoding human OCTN2 maps to chromosome 5q31. Mutations in the gene encoding OCTN2 leads to systemic carnitine deficiency (SCD), an autosomal recessive disorder characterized by cardiomyopathy, skeletal myopathy, lethargy, hypoglycemia and hyperammonemia.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

SLC22A5
Polyclonal
Unconjugated
SLC22A5
CDSP; CT1; high-affinity carnitine transporter; high-affinity sodium dependent carnitine cotransporter; high-affinity sodium-dependent carnitine cotransporter; integral membrane transport protein; juvenile visceral steatosis; jvs; Lstpl; Octn2; OCTN2VT; Organic cation/carnitine transporter 2; S22A5; SLC22A5; solute carrier family 22 (organic cation transporter), member 5; solute carrier family 22 (organic cation/carnitine transporter), member 5; solute carrier family 22 member 5; solute carrier family 22, member 5; UST2r
Rabbit
Antigen Affinity Chromatography
RUO
20520, 29726
-20°C
Lyophilized
Western Blot
500 μg/mL
PBS with 5mg BSA and 0.05mg sodium azide, 0.05mg thimerosal
O70594, Q9Z0E8
SLC22A5
A synthetic peptide corresponding to a sequence at the C-terminus of mouse Solute carrier family 22 member 5 (531-547aa KQWQIQSQTRMQKDGEE).
100 μg
Primary
Mouse, Rat
Antibody
IgG
Product Suggestions

Product Suggestions

Videos
Safety and Handling

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
SDS
Documents

Documents

Product Certifications
Promotions

Promotions

Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Your feedback has been submitted: Thank you for helping us improve our website.