Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Invitrogen™ SLC22A5 Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA580016
Description
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: Rat Kidney Tissue, Rat Skeletal Muscles Tissue, Mouse Liver Tissue, HEPA Cell, NIH3T3 Cell.
Carnitine (b-hydroxy-g-trimethylaminobutyrate) is a small, highly polar compound that aids in the b-oxidation of long-chain fatty acids. Organic cation/carnitine transporters (OCTN) assist in the elimination of cationic compounds, including xenobiotics, and transport carnitine for reabsorption in the kidney. Similar to organic cation transporters (OCT), OCTN proteins localize to the plasma membrane of epithelial cells. OCTN1 is expressed in kidney, trachea, bone marrow and fetal liver. OCTN2 is abundantly expressed in kidney, skeletal muscle, placenta and heart. OCTN3 is strongly expressed in testis and weakly expressed in kidney. The gene encoding human OCTN1 maps to chromosome 5 and the gene encoding human OCTN2 maps to chromosome 5q31. Mutations in the gene encoding OCTN2 leads to systemic carnitine deficiency (SCD), an autosomal recessive disorder characterized by cardiomyopathy, skeletal myopathy, lethargy, hypoglycemia and hyperammonemia.
Specifications
SLC22A5 | |
Polyclonal | |
Unconjugated | |
SLC22A5 | |
CDSP; CT1; high-affinity carnitine transporter; high-affinity sodium dependent carnitine cotransporter; high-affinity sodium-dependent carnitine cotransporter; integral membrane transport protein; juvenile visceral steatosis; jvs; Lstpl; Octn2; OCTN2VT; Organic cation/carnitine transporter 2; S22A5; SLC22A5; solute carrier family 22 (organic cation transporter), member 5; solute carrier family 22 (organic cation/carnitine transporter), member 5; solute carrier family 22 member 5; solute carrier family 22, member 5; UST2r | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
20520, 29726 | |
-20°C | |
Lyophilized |
Western Blot | |
500 μg/mL | |
PBS with 5mg BSA and 0.05mg sodium azide, 0.05mg thimerosal | |
O70594, Q9Z0E8 | |
SLC22A5 | |
A synthetic peptide corresponding to a sequence at the C-terminus of mouse Solute carrier family 22 member 5 (531-547aa KQWQIQSQTRMQKDGEE). | |
100 μg | |
Primary | |
Mouse, Rat | |
Antibody | |
IgG |
Safety and Handling
WARNING: Cancer - www.P65Warnings.ca.gov
Product Content Correction
Your input is important to us. Please complete this form to provide feedback related to the content on this product.
Product Title
Spot an opportunity for improvement?Share a Content Correction