Slc22a5 Rabbit anti-Human, Polyclonal, Bioss

Catalog No.	Quantity
50-198-8314	100 μL

Catalog No. 50-198-8314 Supplier Bioss Supplier No. BS8149R

Description

Rabbit Polyclonal Antibody

Carnitine (b-hydroxy-g-trimethylaminobutyrate) is a small, highly polar compound that aids in the b-oxidation of long-chain fatty acids. Organic cation/carnitine transporters (OCTN) assist in the elimination of cationic compounds, including xenobiotics, and transport carnitine for reabsorption in the kidney. Similar to organic cation transporters (OCT), OCTN proteins localize to the plasma membrane of epithelial cells. OCTN1 is expressed in kidney, trachea, bone marrow and fetal liver. OCTN2 is abundantly expressed in kidney, skeletal muscle, placenta and heart. OCTN3 is strongly expressed in testis and weakly expressed in kidney. The gene encoding human OCTN1 maps to chromosome 5 and the gene encoding human OCTN2 maps to chromosome 5q31. Mutations in the gene encoding OCTN2 leads to systemic carnitine deficiency (SCD), an autosomal recessive disorder characterized by cardiomyopathy, skeletal myopathy, lethargy, hypoglycemia and hyperammonemia.

Specifications

• Antigen: Slc22a5
• Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 1 μg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene: SLC22A5
• Gene Accession No.: O76082
• Gene Alias: CDSP; CT1; high-affinity carnitine transporter; high-affinity sodium dependent carnitine cotransporter; High-affinity sodium-dependent carnitine cotransporter; integral membrane transport protein; juvenile visceral steatosis; jvs; Lstpl; Octn2; OCTN2VT; Organic cation/carnitine transporter 2; S22A5; SLC22A5; solute carrier family 22 (organic cation transporter), member 5; solute carrier family 22 (organic cation/carnitine transporter), member 5; Solute carrier family 22 member 5; solute carrier family 22, member 5; UST2r
• Gene Symbols: SLC22A5
• Host Species: Rabbit
• Immunogen: KLH conjugated synthetic peptide derived from human Slc22a5.
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 6584
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG