Invitrogen™ SLC25A14 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA542431

Catalog No. PIPA542431

Description

Peptide sequence: SIVAEFGTFP VDLTKTRLQV QGQSIDARFK EIKYRGMFHA LFRICKEEGV Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%; Yeast: 79%; Zebrafish: 100%.

Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known. UCPs contain the three homologous protein domains of MACPs. This gene is widely expressed in many tissues with the greatest abundance in brain and testis. The gene product has an N-terminal hydrophobic domain that is not present in other UCPs. Two splice variants have been found for this gene.

Specifications

• Antigen: SLC25A14
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SLC25A14
• Gene Alias: BMCP1; BMCP-1; brain mitochondrial carrier protein 1; MGC137654 protein; mitochondrial uncoupling protein 5; slc25a14; solute carrier family 25 (mitochondrial carrier, brain), member 14; solute carrier family 25 member 14; UCP 5; Ucp5; UCP5L; UCP5S; uncoupling protein 5; UNQ791/PRO1682; zgc:55596
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 9016
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: O95258
• Gene Symbols: SLC25A14
• Immunogen: Synthetic peptide directed towards the N-terminal of human SLC25A14 (aa 51-100).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG