Invitrogen™ SLC25A20 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA589550

Catalog No. PIPA589550

Description

Positive Samples: Mouse liver; Cellular Location: Mitochondrion inner membrane, Multi-pass membrane protein Immunogen sequence: TQPPSLPGQP PMYSGT.

SLC25A20 is one of several closely related mitochondrial-membrane carrier proteins that shuttle substrates between cytosol and the intramitochondrial matrix space. It mediates the transport of acylcarnitines into mitochondrial matrix for their oxidation by the mitochondrial fatty acid-oxidation pathway. Mutations in this gene are associated with carnitine-acylcarnitine translocase deficiency, which can cause a variety of pathological conditions such as hypoglycemia, cardiac arrest, hepatomegaly, hepatic dysfunction and muscle weakness, and is usually lethal in new born and infants. This gene product is one of several closely related mitochondrial-membrane carrier proteins that shuttle substrates between cytosol and the intramitochondrial matrix space. This protein mediates the transport of acylcarnitines into mitochondrial matrix for their oxidation by the mitochondrial fatty acid-oxidation pathway. Mutations in this gene are associated with carnitine-acylcarnitine translocase deficiency, which can cause a variety of pathological conditions such as hypoglycemia, cardiac arrest, hepatomegaly, hepatic dysfunction and muscle weakness, and is usually lethal in new born and infants.

Specifications

• Antigen: SLC25A20
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SLC25A20
• Gene Alias: 1110007P09Rik; C78826; CAC; CACT; carnitine/acylcarnitine carrier protein; carnitine/acylcarnitine translocase; mCAC; mitochondrial carnitine/acylcarnitine carrier protein; mitochondrial carnitine-acylcarnitine translocase; slc25a20; solute carrier family 25 (carnitine/acylcarnitine translocase), member 20; solute carrier family 25 (mitochondrial carnitine/acylcarnitine translocase), member 20; solute carrier family 25 member 20; Unknown (protein for MGC:128410); zgc:77760
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 117035, 57279, 788
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 0.44 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: O43772, P97521, Q9Z2Z6
• Gene Symbols: SLC25A20
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human SLC25A20 (NP_0003781).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG