Invitrogen™ SLC25A20 Polyclonal Antibody

Catalog No.	Quantity
PIPA589550	100 μL

Catalog No. PIPA589550 Supplier Invitrogen™ Supplier No. PA589550

Description

Rabbit Polyclonal Antibody

Positive Samples: Mouse liver; Cellular Location: Mitochondrion inner membrane, Multi-pass membrane protein Immunogen sequence: TQPPSLPGQP PMYSGT.

SLC25A20 is one of several closely related mitochondrial-membrane carrier proteins that shuttle substrates between cytosol and the intramitochondrial matrix space. It mediates the transport of acylcarnitines into mitochondrial matrix for their oxidation by the mitochondrial fatty acid-oxidation pathway. Mutations in this gene are associated with carnitine-acylcarnitine translocase deficiency, which can cause a variety of pathological conditions such as hypoglycemia, cardiac arrest, hepatomegaly, hepatic dysfunction and muscle weakness, and is usually lethal in new born and infants. This gene product is one of several closely related mitochondrial-membrane carrier proteins that shuttle substrates between cytosol and the intramitochondrial matrix space. This protein mediates the transport of acylcarnitines into mitochondrial matrix for their oxidation by the mitochondrial fatty acid-oxidation pathway. Mutations in this gene are associated with carnitine-acylcarnitine translocase deficiency, which can cause a variety of pathological conditions such as hypoglycemia, cardiac arrest, hepatomegaly, hepatic dysfunction and muscle weakness, and is usually lethal in new born and infants.

Specifications

• Antigen: SLC25A20
• Applications: ELISA, Western Blot
• Classification: Polyclonal
• Concentration: 0.44 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
• Gene: SLC25A20
• Gene Accession No.: O43772, P97521, Q9Z2Z6
• Gene Alias: 1110007P09Rik; C78826; CAC; CACT; carnitine/acylcarnitine carrier protein; carnitine/acylcarnitine translocase; mCAC; mitochondrial carnitine/acylcarnitine carrier protein; mitochondrial carnitine-acylcarnitine translocase; slc25a20; solute carrier family 25 (carnitine/acylcarnitine translocase), member 20; solute carrier family 25 (mitochondrial carnitine/acylcarnitine translocase), member 20; solute carrier family 25 member 20; Unknown (protein for MGC:128410); zgc:77760
• Gene Symbols: SLC25A20
• Host Species: Rabbit
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human SLC25A20 (NP_0003781).
• Purification Method: Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 117035, 57279, 788
• Target Species: Human, Mouse, Rat
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG