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Invitrogen™ SLC25A5 Polyclonal Antibody
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Catalog No. PIPA575909
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100 μL
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PIPA575909 100 μL
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Catalog No. PIPA575909 Supplier Invitrogen™ Supplier No. PA575909
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Description

Rabbit Polyclonal Antibody

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Adenine nucleotide translocator (ANT) and the voltage-dependent anion-selective channel proteins 1 and 2 (VDAC1 and VDAC2) are components of the permeability transition pore complex (PTPC) of the mitochondrial inner and outer membranes, respectively. Formation of PTPCs, the subsequent dissipation of mitochondrial inner membrane potential and release of cytochrome c through the outer mitochondrial membrane are critical events in the early stages of apoptosis. Bax, a proapoptotic protein, has been shown to act upon ANT to induce the dissipation of mitochondrial inner membrane potential. ANT1 has a role in the maintenance of mitochondrial DNA by catalyzing the exchange of ADP and ATP across the mitochondrial inner membrane.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SLC25A5
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% sodium azide; pH 7.3
Gene SLC25A5
Gene Accession No. P05141, P51881, Q09073
Gene Alias 2F1; AAC2; Adenine nucleotid translocator 2 fibroblast isoform (ATP-ADP carrier protein); Adenine nucleotid translocator 2, fibroblast isoform (ATP-ADP carrier protein); Adenine nucleotide translocator 2; adenine nucleotide translocator 2 (fibroblast); adenine nucleotide translocator 2 fibroblast isoform (ATP-ADP carrier protein); adenine nucleotide translocator 2, fibroblast isoform (ATP-ADP carrier protein); ADP,ATP carrier protein 2; ADP,ATP carrier protein, fibroblast isoform; ADP/ATP translocase 2; ADP/ATP translocase 2, N-terminally processed; ANT 2; ANT2; Slc25a5; solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 5; solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5; solute carrier family 25 member 5; T2; T3
Gene Symbols SLC25A5
Host Species Rabbit
Immunogen Synthetic peptide corresponding to residues in Human SLC25A5.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11740, 25176, 292
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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