Invitrogen™ SLC26A2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA563524

Catalog No. PIPA563524

Description

Immunogen sequence: ESKEQHNVSP RDSAEGNDSY PSGIHLELQR ESSTDFKQFE TNDQCRPYHR ILIERQEKSD TNFKEFVIKK LQKNCQCSP Highest antigen sequence identity to the following orthologs: Mouse - 52%, Rat - 51%.

The SLC26 family is comprised of sulfate/anion transporters that are well conserved in both their genomic and protein structures, yet have markedly different tissue expression patterns. Members of the SLC26 family can mediate the electroneutral exchange of Cl- for HCO3- across the plasma membrane of mammalian cells. SLC26A2 (solute carrier family 26, member 2), also known as DTD, EDM4, DTDST, MST153, D5S1708 or MSTP157, is a 739 amino acid diastrophic dysplasia sulfate transporter belonging to the SLC26A/SulP transporter family. Ubiquitously expressed, SLC26A2 may play a role in endochondral bone formation. SLC26A2 is a transmembrane glycoprotein implicated in the pathogenesis of several human chondrodysplasias and is critical for sulfation of proteoglycans and matrix organization in cartilage.

Specifications

• Antigen: SLC26A2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SLC26A2
• Gene Alias: D5S1708; Diastrophic dysplasia protein; diastrophic dysplasia protein homolog; Dtd; DTD sulfate transporter; DTDST; EDM4; MST153; MSTP157; SLC26A2; solute carrier family 26 (anion exchanger), member 2; solute carrier family 26 (sulfate transporter), member 2; solute carrier family 26 member 2; solute carrier protein 26a2; ST-OB; sulfate anion transporter 1; sulfate transporter
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1836
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.3 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P50443
• Gene Symbols: SLC26A2
• Immunogen: Recombinant protein corresponding to Human SLC26A2. Recombinant protein control fragment (Product #RP-103884).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG