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Invitrogen™ SLC28A2 Polyclonal Antibody
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Catalog No. PIPA536941
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PIPA536941 100 μL
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Catalog No. PIPA536941 Supplier Invitrogen™ Supplier No. PA536941
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Rabbit Polyclonal Antibody

This antibody detects endogenous protein at a molecular weight of 72 kDa. Purity is >95% by SDS-PAGE.

The concentrative nucleoside transporter (CNT) family comprises three members: CNT1, CNT2 and CNT3. CNT2 participates in the absorption and disposition of endogenous nucleosides and mediates the first step of nucleotide biosynthesis. CNT2 levels are highly dependent on insulin (but not glucose) concentration, and the protein is under the control of the Adenosine 1 receptor. CNT family members are imperative in the response of cells to a variety of anticancer and antiviral nucleoside analogs, as the CNT proteins modulate their entry into target tissues. Increasing evidence also suggests that CNT2 may have a role in energy metabolism because activation of CNT2 relies on the opening of ATP-sensitive K+ channels.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SLC28A2
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
Gene SLC28A2
Gene Accession No. O43868, O88627, Q62773
Gene Alias 2010208B10Rik; B430217P18; BB152493; CNT 2; CNT2; CNT-2; Concentrative nucleoside transporter 2; HCNT2; HsT17153; Na(+)/nucleoside cotransporter 2; purine-selective Na+ nucleoside cotransporter; rCNT2; Slc28a2; sodium/nucleoside cotransporter 2; sodium/purine nucleoside cotransporter; Sodium/purine nucleoside co-transporter; Sodium-coupled nucleoside transporter 2; solute carrier family 28 (concentrative nucleoside transporter), member 2; solute carrier family 28 (sodium-coupled nucleoside transporter), member 2; solute carrier family 28 member 2; solute carrier family 28, member 2; SPNT; SPNT1
Gene Symbols SLC28A2
Host Species Rabbit
Immunogen Synthetic peptide corresponding to amino acids 417-462 of human SLC28A2.
Purification Method Antigen Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 269346, 60423, 9153
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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