Invitrogen™ SLC29A3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA566109

Catalog No. PIPA566109

Description

Immunogen sequence: KEYWMFKLRNS SSPATGEDPE GSDILNYFE Highest antigen sequence identity to the following orthologs - mouse 80%, rat 80%.

SLC29A3 is a member of the equilibrative nucleoside transporter family which plays a key role in nucleoside and nucleobase uptake for salvage pathways of nucleotide synthesis. SLC29A3 is a transmembrane glycoprotein that localizes to the lysosomal membrane and is a broad selectivity, low affinity nucleoside transporter. Mutations in the SLC29A3 gene have been associated with H syndrome, which is characterized by cutaneous hyperpigmentation and hypertrichosis, hepatosplenomegaly, heart anomalies, and hypogonadism. A related disorder, PHID (pigmented hypertrichosis with insulin-dependent diabetes mellitus), has also been associated with mutations at this locus.

Specifications

• Antigen: SLC29A3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SLC29A3
• Gene Alias: 4933435C21Rik; AW987637; Ent3; Equilibrative nucleoside transporter 3; HCLAP; hENT3; HJCD; mENT3; PHID; Slc29a3; solute carrier family 29 (equilibrative nucleoside transporter), member 3; solute carrier family 29 (nucleoside transporters), member 3; solute carrier family 29 member 3; UNQ717/PRO1380
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 55315
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 0.05 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9BZD2
• Gene Symbols: SLC29A3
• Immunogen: Recombinant Human SLC29A3. Recombinant protein control fragment (Product #RP-105085).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG