Invitrogen™ SLC2A13 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA597325

Catalog No. PIPA597325

Description

Immunogen sequence: LHTAEYLTYY GAFFLYAGFA AVGLLFIYGC LPETKGKKLE EIESLFDNRL CTCGTSDSDE GRYIEYIRVK GSNYHLSDND ASDVE; Positive Samples: HeLa, SH-SY5Y, HepG2, NCI-H460, HT-1080, K-562, Mouse kidney, Mouse pancreas, Rat kidney; Cellular Location: Membrane, Multi-pass membrane protein.

SLC2A13 (solute carrier family 2 (facilitated glucose transporter), member 13) is a 648 multi-pass membrane protein that belongs to the major facilitator superfamily and the sugar transporter family. SLC2A13 is a H+-myo-inositol cotransporter that can also transport related stereoisomers. Human SLC2A13 shares 90% identity with its rat homolog. The rat sequence has 12 transmembrane domains, 3 N-glycosylation sites, several motifs important for glucose transport activity, and an endoplasmic reticulum retention signal and dileucine internalization signal in the N-terminal region. SLC2A13 has been shown to specifically transport myoinositol but not hexoses, and decreasing the pH of the extracellular medium from 7.0 to 5.0 markedly increased transport activity.

Specifications

• Antigen: SLC2A13
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SLC2A13
• Gene Alias: 6530403A04; A630029G22Rik; AI505012; Gm308; h(+)-myo-inositol cotransporter; H(+)-myo-inositol symporter; Hmit; proton (H+) myo-inositol symporter; proton myo-inositol cotransporter; proton myo-inositol symporter; SLC2A13; solute carrier family 2 (facilitated glucose transporter), member 13; solute carrier family 2 member 13
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 114134, 171147, 239606
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 0.35 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q3UHK1, Q921A2, Q96QE2
• Gene Symbols: SLC2A13
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 564-648 of human SLC2A13 (NP_4431173).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG