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Invitrogen™ SLC2A13 Polyclonal Antibody
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Catalog No. PIPA597325
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PIPA597325 100 μL
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Catalog No. PIPA597325 Supplier Invitrogen™ Supplier No. PA597325
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: LHTAEYLTYY GAFFLYAGFA AVGLLFIYGC LPETKGKKLE EIESLFDNRL CTCGTSDSDE GRYIEYIRVK GSNYHLSDND ASDVE; Positive Samples: HeLa, SH-SY5Y, HepG2, NCI-H460, HT-1080, K-562, Mouse kidney, Mouse pancreas, Rat kidney; Cellular Location: Membrane, Multi-pass membrane protein.

SLC2A13 (solute carrier family 2 (facilitated glucose transporter), member 13) is a 648 multi-pass membrane protein that belongs to the major facilitator superfamily and the sugar transporter family. SLC2A13 is a H+-myo-inositol cotransporter that can also transport related stereoisomers. Human SLC2A13 shares 90% identity with its rat homolog. The rat sequence has 12 transmembrane domains, 3 N-glycosylation sites, several motifs important for glucose transport activity, and an endoplasmic reticulum retention signal and dileucine internalization signal in the N-terminal region. SLC2A13 has been shown to specifically transport myoinositol but not hexoses, and decreasing the pH of the extracellular medium from 7.0 to 5.0 markedly increased transport activity.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SLC2A13
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.35 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene SLC2A13
Gene Accession No. Q3UHK1, Q921A2, Q96QE2
Gene Alias 6530403A04; A630029G22Rik; AI505012; Gm308; h(+)-myo-inositol cotransporter; H(+)-myo-inositol symporter; Hmit; proton (H+) myo-inositol symporter; proton myo-inositol cotransporter; proton myo-inositol symporter; SLC2A13; solute carrier family 2 (facilitated glucose transporter), member 13; solute carrier family 2 member 13
Gene Symbols SLC2A13
Host Species Rabbit
Immunogen Recombinant protein (or fragment)
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 114134, 171147, 239606
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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