Invitrogen™ SLC30A8 Polyclonal Antibody

Sheep Polyclonal Antibody

Supplier:  Invitrogen™ PA547916

Catalog No. PIPA547916

Description

Reconstitute in sterile PBS to a final concentration of 0.2 mg/mL.

Slc30A8 is a zinc efflux transporter involved in the accumulation of zinc in intracellular vesicles and is expressed at a high level in the pancreas, particularly in islets of Langerhans, and co-localizes with insulin in the secretory pathway granules of the insulin-secreting INS-1 cells. Allelic variants of Slc30A8 have been identified as major genetic risk factors for the development of Type 2 diabetes, but no genetic association has been found with Type 1 diabetes. Slc30A8 expression in b-cells was found to be influenced by cytokine expression, particularly IFN-gamma and IL-1 beta.

Specifications

• Antigen: SLC30A8
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SLC30A8
• Gene Alias: C820002P14Rik; LOW QUALITY PROTEIN: uncharacterized protein slc30a8; Slc30a8; solute carrier family 30 (zinc transporter), member 8; solute carrier family 30 member 8; wu:fe49g03; Zinc transporter 8; zinc transporter 8; LOW QUALITY PROTEIN: zinc transporter 8; zinc transporter ZnT-8; Znt8; ZnT-8
• Host Species: Sheep
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 169026
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.2 mg/mL
• Formulation: PBS with 5% trehalose and No Preservative
• Gene Accession No.: Q8IWU4
• Gene Symbols: SLC30A8
• Immunogen: E. coli-derived recombinant human ZnT-8 Lys268-Pro359.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG