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Invitrogen™ SLC30A8 Polyclonal Antibody
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Catalog No. PIPA584993
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100 μL
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Catalog No. Quantity
PIPA584993 100 μL
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Catalog No. PIPA584993 Supplier Invitrogen™ Supplier No. PA584993
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: LSAHVATAAS RDSQVVRREI AKALSKSFTM HSLTIQMESP VDQDPDCLFC EDPCD Highest antigen sequence indentity to the following orthologs: Mouse - 73%, Rat - 73%.

Slc30A8 is a zinc efflux transporter involved in the accumulation of zinc in intracellular vesicles and is expressed at a high level in the pancreas, particularly in islets of Langerhans, and co-localizes with insulin in the secretory pathway granules of the insulin-secreting INS-1 cells. Allelic variants of Slc30A8 have been identified as major genetic risk factors for the development of Type 2 diabetes, but no genetic association has been found with Type 1 diabetes. Slc30A8 expression in b-cells was found to be influenced by cytokine expression, particularly IFN-gamma and IL-1 beta.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SLC30A8
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.3 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene SLC30A8
Gene Accession No. Q8IWU4
Gene Alias C820002P14Rik; LOW QUALITY PROTEIN: uncharacterized protein slc30a8; Slc30a8; solute carrier family 30 (zinc transporter), member 8; solute carrier family 30 member 8; wu:fe49g03; Zinc transporter 8; zinc transporter 8; LOW QUALITY PROTEIN: zinc transporter 8; zinc transporter ZnT-8; Znt8; ZnT-8
Gene Symbols SLC30A8
Host Species Rabbit
Immunogen Recombinant protein fragment of Human SLC30A8 (Product #RP-108278)
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 169026
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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