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Invitrogen™ Slc30A8 Polyclonal Antibody
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Catalog No. PIPA5103252
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100 μL
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PIPA5103252 100 μL
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Catalog No. PIPA5103252 Supplier Invitrogen™ Supplier No. PA5103252
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total SLC30A8.

Slc30A8 is a zinc efflux transporter involved in the accumulation of zinc in intracellular vesicles and is expressed at a high level in the pancreas, particularly in islets of Langerhans, and co-localizes with insulin in the secretory pathway granules of the insulin-secreting INS-1 cells. Allelic variants of Slc30A8 have been identified as major genetic risk factors for the development of Type 2 diabetes, but no genetic association has been found with Type 1 diabetes. Slc30A8 expression in b-cells was found to be influenced by cytokine expression, particularly IFN-gamma and IL-1 beta.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Slc30A8
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene SLC30A8
Gene Accession No. Q8IWU4
Gene Alias C820002P14Rik; LOW QUALITY PROTEIN: uncharacterized protein slc30a8; Slc30a8; solute carrier family 30 (zinc transporter), member 8; solute carrier family 30 member 8; wu:fe49g03; Zinc transporter 8; zinc transporter 8; LOW QUALITY PROTEIN: zinc transporter 8; zinc transporter ZnT-8; Znt8; ZnT-8
Gene Symbols SLC30A8
Host Species Rabbit
Immunogen A synthesized peptide derived from human SLC30A8(Accession Q8IWU4), corresponding to amino acid residues I179-I229.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 169026
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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