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  6. SLC30A8/ZNT8 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech 

SLC30A8/ZNT8 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
SDP

Catalog No. 50554319 Shop All Proteintech Group Inc Products
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50-554-319 150 μL
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Catalog No. 50-554-319 Supplier Proteintech Group Inc Supplier No. 161691AP150UL
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Description

Rabbit Polyclonal Antibody

Slc30A8 is a zinc efflux transporter involved in the accumulation of zinc in intracellular vesicles and is expressed at a high level in the pancreas, particularly in islets of Langerhans, and co-localizes with insulin in the secretory pathway granules of the insulin-secreting INS-1 cells. Allelic variants of Slc30A8 have been identified as major genetic risk factors for the development of Type 2 diabetes, but no genetic association has been found with Type 1 diabetes. Slc30A8 expression in b-cells was found to be influenced by cytokine expression, particularly IFN-gamma and IL-1 beta.

Specifications

Antigen SLC30A8/ZNT8
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.22 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene SLC30A8
Gene Accession No. P0CE46, Q8BGG0, Q8IWU4
Gene Alias SLC30A8, Zinc transporter 8, ZnT 8, ZNT8
Gene Symbols Slc30a8
Host Species Rabbit
Immunogen Peptide
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 169026, 239436, 299903
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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