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Invitrogen™ SLC39A4 Polyclonal Antibody
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Catalog No. PIPA578528
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PIPA578528 100 μL
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Catalog No. PIPA578528 Supplier Invitrogen™ Supplier No. PA578528
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Description

Rabbit Polyclonal Antibody

Positive Control: SLC39A4-transfected 293T Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The zinc transporter ZIP4, also known as SLC39A4, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. ZIP4 was initially identified as zinc-uptake transporter in the intestine and as a candidate gene for acrodermatitis enteropathica (AE), a rare inherited defect in the absorption of dietary zinc. Similar to other ZIP family members, aberrant expression of ZIP4 has been linked to cancer, specifically the progression and aggressiveness of pancreatic cancer. ZIP4 expression has also been shown to be activated in hepatocellular carcinomas, acting to repress apoptosis, enhance cell cycle and increase migration, suggesting ZIP4 may play a role in multiple types of cancers.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SLC39A4
Applications Western Blot
Classification Polyclonal
Concentration 0.32 mg/mL
Conjugate Unconjugated
Formulation PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene Slc39a4
Gene Accession No. Q6P5W5
Gene Alias 1600025H15Rik; activated in W/Wv mouse stomach 2; AEZ; AU041686; AWMS2; EMBL:AAI27515.1}; mAWMS2; SLC39A4; slc39a4 {ECO:0000312; solute carrier family 39 (zinc transporter), member 4; solute carrier family 39 member 4; Zinc transporter ZIP4; Zip4; ZIP-4; Zrt- and Irt-like protein 4
Gene Symbols Slc39a4
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the Extracellular domain of human SLC39A4. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 55630
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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