Invitrogen™ SLC39A5 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA542522

Catalog No. PIPA542522

Description

Peptide sequence: MGSPVSHLLA GFCVWVVLGW VGGSVPNLGP AEQEQNHYLA QLFGLYGENG Sequence homology: Cow: 86%; Dog: 93%; Guinea Pig: 93%; Horse: 86%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%.

The zinc transporter ZIP5, also known as SLC39A5, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. ZIP5 is closely related to ZIP4, and is found in many of the same tissues, including intestine, pancreas, liver, and kidney, but unlike ZIP4, ZIP5 localizes to the basolateral membrane in kidney cells and its activity is not downregulated by zinc repletion. Recent evidence suggests that ZIP4 and ZIP5 are reciprocally regulated, with translation of ZIP5 mRNA decreasing and ZIP5 protein being rapidly internalized and degraded in response to zinc deficiency.

Specifications

• Antigen: SLC39A5
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SLC39A5
• Gene Alias: 1810013D05Rik; 2010205A06Rik; LZT-Hs7; MGC34778; MYP24; SLC39A5; solute carrier family 39 (metal ion transporter), member 5; solute carrier family 39 (zinc transporter), member 5; solute carrier family 39 member 5; Zinc transporter ZIP5; Zip5; ZIP-5; zrt- and Irt-like protein 5
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 283375
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Immunohistochemistry, Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: Q6ZMH5
• Gene Symbols: SLC39A5
• Immunogen: Synthetic peptide directed towards the N-terminal of human SLC39A5 (aa 2-51).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov