SLC39A6 Rabbit anti-Human, Polyclonal, Bethyl Laboratories

Catalog No.	Quantity
50-157-0565	100 μL

Catalog No. 50-157-0565 Supplier Bethyl Laboratories, Inc Supplier No. A305490A

Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt.

The zinc transporter ZIP6, also known as SLC39A6, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. ZIP6 was initially identified as LIV-1, an estrogen-regulated gene that has been implicated in metastatic breast cancer. Elevated ZIP6 expression has also been reported in human cervical cancer and the HeLa cell line; down-regulation of ZIP6 expression in HeLa by RNAi inhibited cell proliferation, colony formation, migration and invasiveness, as well as decreasing Snail and Slug levels, suggesting ZIP6 plays a regulatory role on the ERK1/2-Snail/Slug pathway.

Specifications

• Antigen: SLC39A6
• Applications: Immunoprecipitation
• Classification: Polyclonal
• Concentration: 1 mg/ml
• Conjugate: Unconjugated
• Formulation: phosphate, tris citrate with 0.09% sodium azide; pH 7-8
• Gene: SLC39A6
• Gene Accession No.: Q13433
• Gene Alias: LIV-1; LIV-1 protein, estrogen regulated; ZIP-6; estrogen-regulated protein LIV-1; solute carrier family 39 (metal ion transporter), member 6; solute carrier family 39 member 6; zinc transporter ZIP6; zrt- and Irt-like protein 6
• Gene Symbols: SLC39A6
• Host Species: Rabbit
• Immunogen: Between 125 and 175
• Purification Method: Antigen affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 25800
• Target Species: Human
• Content And Storage: 4° C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG