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Invitrogen™ SLC4A8 Polyclonal Antibody
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Catalog No. PIPA527880
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100 μL
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Catalog No. Quantity
PIPA527880 100 μL
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Catalog No. PIPA527880 Supplier Invitrogen™ Supplier No. PA527880
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: IMR32, U87-MG. Predicted reactivity: Mouse (92%), Rat (91%), Rhesus Monkey (99%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Mediates electroneutral sodium- and carbonate-dependent choride-HCO3(-) exchange with a Na(+):HCO3(-) stoichiometry of 2:1. Plays a major role in pH regulation in neurons. May be involved in cell pH regulation by transporting HCO3(-) from blood to cell. Enhanced expression in severe acid stress could be important for cell survival by mediating the influx of HCO3(-) into the cells. Also mediates lithium-dependent HCO3(-) cotransport. May be regulated by osmolarity.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SLC4A8
Applications Western Blot
Classification Polyclonal
Concentration 0.99 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene Slc4a8
Gene Accession No. Q2Y0W8
Gene Alias AW493845; C230026C11; Electroneutral Na(+)-driven Cl-HCO3 exchanger; electroneutral Na+-driven Cl-HCO3 exchanger; Electroneutral sodium bicarbonate exchanger 1; KIAA0739; k-NBC3; kNBC-3; Na-driven Cl-HCO3 exchanger NDCBE1-A; Na-driven Cl-HCO3 exchanger NDCBE1-B; Na-driven Cl-HCO3 exchanger NDCBE1-C; NBC; NBC3; NDCBE; NDCBE1; RGD:735164}; Slc4a8; slc4a8 {ECO:0000312; sodium bicarbonate cotransporter isoform 3 kNBC-3; solute carrier family 4 (anion exchanger), member 8; solute carrier family 4 member 8; solute carrier family 4, sodium bicarbonate cotransporter, member 8
Gene Symbols Slc4a8
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the Extracellular domain of human SLC4A8. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9498
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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