Invitrogen™ SLC4A8 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5139959

Catalog No. PIPA5139959

Description

Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user. Immunogen sequence: ELEGHRTLYV GVRMPLGRQS HRHHRTHGQK HRRRGRGKGA SQGEEGLEAL AHDTPSQRV.

Mediates electroneutral sodium- and carbonate-dependent choride-HCO3(-) exchange with a Na(+):HCO3(-) stoichiometry of 2:1. Plays a major role in pH regulation in neurons. May be involved in cell pH regulation by transporting HCO3(-) from blood to cell. Enhanced expression in severe acid stress could be important for cell survival by mediating the influx of HCO3(-) into the cells. Also mediates lithium-dependent HCO3(-) cotransport. May be regulated by osmolarity.

Specifications

• Antigen: SLC4A8
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Slc4a8
• Gene Alias: AW493845; C230026C11; Electroneutral Na(+)-driven Cl-HCO3 exchanger; electroneutral Na+-driven Cl-HCO3 exchanger; Electroneutral sodium bicarbonate exchanger 1; KIAA0739; k-NBC3; kNBC-3; Na-driven Cl-HCO3 exchanger NDCBE1-A; Na-driven Cl-HCO3 exchanger NDCBE1-B; Na-driven Cl-HCO3 exchanger NDCBE1-C; NBC; NBC3; NDCBE; NDCBE1; RGD:735164}; Slc4a8; slc4a8 {ECO:0000312; sodium bicarbonate cotransporter isoform 3 kNBC-3; solute carrier family 4 (anion exchanger), member 8; solute carrier family 4 member 8; solute carrier family 4, sodium bicarbonate cotransporter, member 8
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 9498
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunocytochemistry
• Concentration: 0.4 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q2Y0W8
• Gene Symbols: Slc4a8
• Immunogen: Recombinant protein corresponding to Human SLC4A8. Recombinant protein control fragment (Product #RP-109658).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG