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Invitrogen™ SLC4A8 Polyclonal Antibody
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Catalog No. PIPA5139959
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100 μL
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PIPA5139959 100 μL
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Catalog No. PIPA5139959 Supplier Invitrogen™ Supplier No. PA5139959
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Description

Rabbit Polyclonal Antibody

Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user. Immunogen sequence: ELEGHRTLYV GVRMPLGRQS HRHHRTHGQK HRRRGRGKGA SQGEEGLEAL AHDTPSQRV Highest antigen sequence indentity to the following orthologs: Mouse - 98%, Rat - 97%.

Mediates electroneutral sodium- and carbonate-dependent choride-HCO3(-) exchange with a Na(+):HCO3(-) stoichiometry of 2:1. Plays a major role in pH regulation in neurons. May be involved in cell pH regulation by transporting HCO3(-) from blood to cell. Enhanced expression in severe acid stress could be important for cell survival by mediating the influx of HCO3(-) into the cells. Also mediates lithium-dependent HCO3(-) cotransport. May be regulated by osmolarity.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SLC4A8
Applications Immunocytochemistry
Classification Polyclonal
Concentration 0.4 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Slc4a8
Gene Accession No. Q2Y0W8
Gene Alias AW493845; C230026C11; Electroneutral Na(+)-driven Cl-HCO3 exchanger; electroneutral Na+-driven Cl-HCO3 exchanger; Electroneutral sodium bicarbonate exchanger 1; KIAA0739; k-NBC3; kNBC-3; Na-driven Cl-HCO3 exchanger NDCBE1-A; Na-driven Cl-HCO3 exchanger NDCBE1-B; Na-driven Cl-HCO3 exchanger NDCBE1-C; NBC; NBC3; NDCBE; NDCBE1; RGD:735164}; Slc4a8; slc4a8 {ECO:0000312; sodium bicarbonate cotransporter isoform 3 kNBC-3; solute carrier family 4 (anion exchanger), member 8; solute carrier family 4 member 8; solute carrier family 4, sodium bicarbonate cotransporter, member 8
Gene Symbols Slc4a8
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human SLC4A8. Recombinant protein control fragment (Product #RP-109658).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9498
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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