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Invitrogen™ SLC5A5 Monoclonal Antibody (14F), PerCP
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Catalog No. PIMA545491
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100 μg
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Catalog No. Quantity
PIMA545491 100 μg
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Catalog No. PIMA545491 Supplier Invitrogen™ Supplier No. MA545491
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Description

Mouse Monoclonal Antibody

1 μg/mL of MA5-45491 was sufficient for detection of hNIS in 20 μg of transfected COS-7 cell membrane lysate by ECL immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody. Detects approximately 97kDa, non-glycosylated version at 68kDa. Other minor bands associated with hNIS at 160kDa, and degradation products at approximately 30 kDa, and approximately 15kDa.

Human Sodium Iodide Symporter (hNIS) is responsible for iodide concentrating ability within thyroid follicular cells. It is a membrane bound glycoprotein with 13 membrane spanning domains and 14 extramembranous domains. It may represent an autoantigen in thyroid.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SLC5A5
Applications Immunohistochemistry (PFA fixed), Western Blot, Microarray
Classification Monoclonal
Clone 14F
Concentration 1 mg/mL
Conjugate PerCP
Formulation 2.48mM MES, 95.64mM phosphate with 0.5M EDTA and no preservative; pH 7.4
Gene SLC5A5
Gene Accession No. Q63008, Q92911, Q99PN0
Gene Alias Na(+)/I(-) cotransporter; Na(+)/I(-) symporter; Na(+)/I(-)-symporter; Na+/I- symporter; Nis; SLC5A5; sodium iodide symporter; Sodium/iodide cotransporter; sodium-iodide symporter; solute carrier family 5 (sodium iodide symporter), member 5; solute carrier family 5 (sodium/iodide cotransporter), member 5; solute carrier family 5 member 5; solute carrier family 5, member 5; TDH1
Gene Symbols SLC5A5
Host Species Mouse
Immunogen Mannose binding protein hNIS fusion (AA468-643).
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 114479, 114613, 6528
Target Species Human, Mouse, Rat
Content And Storage 4°C
Product Type Antibody
Form Liquid
Isotype IgG1
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