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Invitrogen™ SLC6A11 Polyclonal Antibody
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Catalog No. PIPA558192
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100 μL
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PIPA558192 100 μL
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Catalog No. PIPA558192 Supplier Invitrogen™ Supplier No. PA558192
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Rabbit Polyclonal Antibody

Immunogen sequence: GTLPEKLQKL TTPSTDLKMR GKLGVSPRMV TVNDCDAKLK SDGTIAAITE KETHF Highest antigen sequence identity to the following orthologs: Mouse - 85%, Rat - 87%.

Slc6a11 encode GABA transporters that are sodium- and chloride-dependent members of the solute carrier family 6 (SLC6) and mediate the rapid removal of GABA and maintain low extracellular levels. Four 12-TM domain transporters have been identified and localized to neurons and glia. The protein encoded by the Slc6a11 gene is a sodium-dependent transporter that uptakes gamma-aminobutyric acid (GABA), an inhibitory neurotransmitter, which ends the GABA neurotransmission. Defects in the Slc6a11 gene may result in epilepsy, behavioral problems, or intellectual problems. Two transcript variants encoding different isoforms have been found for the Slc6a11 gene. Diseases associated with SLC6A11 include Tricuspid Valve Stenosis and Pulmonary Valve Insufficiency.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SLC6A11
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene SLC6A11
Gene Accession No. P48066
Gene Alias D930045G19Rik; E130202I16Rik; GABA transporter 3; GABA transporter GAT-3; GABT3; Gabt4; gamma-aminobutyric acid (GABA-A) transporter 4; Gat3; GAT-3; Gat4; GAT-4; Gat-b; SLC6A11; Sodium- and chloride-dependent GABA transporter 3; sodium- and chloride-dependent GABA transporter 4; solute carrier family 6 (neurotransmitter transporter), member 11; solute carrier family 6 (neurotransmitter transporter, GABA), member 11; solute carrier family 6 member 11
Gene Symbols SLC6A11
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human SLC6A11. Recombinant protein control fragment (Product #RP-96336).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6538
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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