SLC6A11 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA577452

Catalog No. PIPA577452

Description

Product is shipped at room temperature as a lyophilized powder and should be stored at -20 °C upon receipt. Reconstitution: add 50 μL of deionized water.

Slc6a11 encode GABA transporters that are sodium- and chloride-dependent members of the solute carrier family 6 (SLC6) and mediate the rapid removal of GABA and maintain low extracellular levels. Four 12-TM domain transporters have been identified and localized to neurons and glia. The protein encoded by the Slc6a11 gene is a sodium-dependent transporter that uptakes gamma-aminobutyric acid (GABA), an inhibitory neurotransmitter, which ends the GABA neurotransmission. Defects in the Slc6a11 gene may result in epilepsy, behavioral problems, or intellectual problems. Two transcript variants encoding different isoforms have been found for the Slc6a11 gene. Diseases associated with SLC6A11 include Tricuspid Valve Stenosis and Pulmonary Valve Insufficiency.

Specifications

• Antigen: SLC6A11
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Slc6a11
• Gene Alias: SLC6A11
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 243616, 79213
• Content And Storage: -20°C
• Form: Lyophilized

• Applications: Western Blot
• Concentration: 0.8 mg/mL
• Formulation: PBS with 1% BSA and 0.05% sodium azide; pH 7.4
• Gene Accession No.: P31647, P31650
• Gene Symbols: Slc6a11
• Immunogen: Peptide (C)REARDKAVHERGH, corresponding to amino acid residues 35-47 of rat GABA Transporter 3
• Quantity: 50 μL
• Primary or Secondary: Primary
• Target Species: Mouse, Rat
• Product Type: Antibody
• Isotype: IgG