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Invitrogen™ SLC6A11 Polyclonal Antibody
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Catalog No. PIPA545004
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100 μL
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PIPA545004 100 μL
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Catalog No. PIPA545004 Supplier Invitrogen™ Supplier No. PA545004
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Description

Rabbit Polyclonal Antibody

Peptide sequence: EGTLPEKLQK LTTPSTDLKM RGKLGVSPRM VTVNDCDAKL KSDGTIAAIT Sequence homology: Cow: 85%; Dog: 92%; Guinea Pig: 92%; Horse: 85%; Human: 100%; Mouse: 77%; Rabbit: 93%; Rat: 92%.

Slc6a11 encode GABA transporters that are sodium- and chloride-dependent members of the solute carrier family 6 (SLC6) and mediate the rapid removal of GABA and maintain low extracellular levels. Four 12-TM domain transporters have been identified and localized to neurons and glia. The protein encoded by the Slc6a11 gene is a sodium-dependent transporter that uptakes gamma-aminobutyric acid (GABA), an inhibitory neurotransmitter, which ends the GABA neurotransmission. Defects in the Slc6a11 gene may result in epilepsy, behavioral problems, or intellectual problems. Two transcript variants encoding different isoforms have been found for the Slc6a11 gene. Diseases associated with SLC6A11 include Tricuspid Valve Stenosis and Pulmonary Valve Insufficiency.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SLC6A11
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide
Gene SLC6A11
Gene Accession No. P48066
Gene Alias D930045G19Rik; E130202I16Rik; GABA transporter 3; GABA transporter GAT-3; GABT3; Gabt4; gamma-aminobutyric acid (GABA-A) transporter 4; Gat3; GAT-3; Gat4; GAT-4; Gat-b; SLC6A11; Sodium- and chloride-dependent GABA transporter 3; sodium- and chloride-dependent GABA transporter 4; solute carrier family 6 (neurotransmitter transporter), member 11; solute carrier family 6 (neurotransmitter transporter, GABA), member 11; solute carrier family 6 member 11
Gene Symbols SLC6A11
Host Species Rabbit
Immunogen Synthetic peptide directed towards the C-terminal of human SLC6A11 (aa 577-626).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6538
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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