Invitrogen™ SLC6A4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5143522

Catalog No. PIPA5143522

Description

SLC6A4 Polyclonal Antibody for Western Blot, ICC/IF, IHC

SERT is an integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. The encoded protein terminates the action of serotonin and recycles it in a sodium-dependent manner. This protein is a target of psychomotor stimulants, such as amphetamines and cocaine, and is a member of the sodium:neurotransmitter symporter family. A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake and may play a role in sudden infant death syndrome, aggressive behavior in Alzheimer disease patients, and depression-susceptibility in people experiencing emotional trauma.

Specifications

• Antigen: SLC6A4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SLC6A4
• Gene Alias: 5 OCD1; 5HT transporter; 5HTT; 5-HTT; 5-HTTLPR; 5-hydroxytryptamine (serotonin) transporter; AI323329; HGNC:11050; hSERT; HTT; Na+/Cl- dependent serotonin transporter; OCD1; OTTHUMP00000163633; serotonin transporter; serotonin transporter 1; Sert; SERT1; Slc6a4; Sodium-dependent serotonin transporter; Sodium-dependent serotonin transporter (5HT transporter) (5HTT); solute carrier family 6 (neurotransmitter transporter serotonin) member 4 (5-hydroxytryptamine (serotonin) transporter); Solute carrier family 6 (neurotransmitter transporter serotonin) member 4 (5-hydroxytryptamine (serotonin) transporter); solute carrier family 6 (neurotransmitter transporter), member 4; solute carrier family 6 (neurotransmitter transporter, serotonin), member 4; solute carrier family 6 member 4; solute carrier family 6, member 4
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 15567, 25553, 282365, 6532
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry, Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 5mM sodium azide
• Gene Accession No.: P31645, P31652, Q60857, Q9XT49
• Gene Symbols: SLC6A4
• Immunogen: KSITPETPTEIPCGDIRLNAV coupled to KLH.
• Quantity: 500 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat, Bovine
• Product Type: Antibody
• Isotype: IgG