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Invitrogen™ SLC6A4 Polyclonal Antibody
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Catalog No. PIPA589657
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100 μL
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PIPA589657 100 μL
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Catalog No. PIPA589657 Supplier Invitrogen™ Supplier No. PA589657
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Description

Rabbit Polyclonal Antibody

Positive Samples: U-251MG, Mouse lung; Cellular Location: Cell membrane, Endomembrane system, Endosome membrane, Multi-pass membrane protein Immunogen sequence: METTPLNSQK QLSACEDGED CQENGVLQKV VPTPGDKVES GQISNGYSAV PSPGAGDDTR HSIPATTTTL VAELHQGERE TWGK.

SERT is an integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. The encoded protein terminates the action of serotonin and recycles it in a sodium-dependent manner. This protein is a target of psychomotor stimulants, such as amphetamines and cocaine, and is a member of the sodium:neurotransmitter symporter family. A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake and may play a role in sudden infant death syndrome, aggressive behavior in Alzheimer disease patients, and depression-susceptibility in people experiencing emotional trauma.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SLC6A4
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.46 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
Gene SLC6A4
Gene Accession No. P31645, P31652, Q60857
Gene Alias 5 OCD1; 5HT transporter; 5HTT; 5-HTT; 5-HTTLPR; 5-hydroxytryptamine (serotonin) transporter; AI323329; HGNC:11050; hSERT; HTT; Na+/Cl- dependent serotonin transporter; OCD1; OTTHUMP00000163633; serotonin transporter; serotonin transporter 1; Sert; SERT1; Slc6a4; Sodium-dependent serotonin transporter; Sodium-dependent serotonin transporter (5HT transporter) (5HTT); solute carrier family 6 (neurotransmitter transporter serotonin) member 4 (5-hydroxytryptamine (serotonin) transporter); Solute carrier family 6 (neurotransmitter transporter serotonin) member 4 (5-hydroxytryptamine (serotonin) transporter); solute carrier family 6 (neurotransmitter transporter), member 4; solute carrier family 6 (neurotransmitter transporter, serotonin), member 4; solute carrier family 6 member 4; solute carrier family 6, member 4
Gene Symbols SLC6A4
Host Species Rabbit
Immunogen Synthetic peptide.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 15567, 25553, 6532
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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