Invitrogen™ SLC6A4 Polyclonal Antibody

Catalog No.	Quantity
PIPA518374	100 μg

Catalog No. PIPA518374 Supplier Invitrogen™ Supplier No. PA518374

Description

Goat Polyclonal Antibody

This antibody is predicted to react with mouse based on sequence homology. This antibody is tested in Peptide ELISA: antibody detection limit dilution 32,000.

SERT is an integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. The encoded protein terminates the action of serotonin and recycles it in a sodium-dependent manner. This protein is a target of psychomotor stimulants, such as amphetamines and cocaine, and is a member of the sodium:neurotransmitter symporter family. A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake and may play a role in sudden infant death syndrome, aggressive behavior in Alzheimer disease patients, and depression-susceptibility in people experiencing emotional trauma.

Specifications

• Antigen: SLC6A4
• Applications: Western Blot, Immunocytochemistry
• Classification: Polyclonal
• Concentration: 0.5 mg/mL
• Conjugate: Unconjugated
• Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
• Gene: SLC6A4
• Gene Accession No.: P31645
• Gene Alias: 5 OCD1; 5HT transporter; 5HTT; 5-HTT; 5-HTTLPR; 5-hydroxytryptamine (serotonin) transporter; AI323329; HGNC:11050; hSERT; HTT; Na+/Cl- dependent serotonin transporter; OCD1; OTTHUMP00000163633; serotonin transporter; serotonin transporter 1; Sert; SERT1; Slc6a4; Sodium-dependent serotonin transporter; Sodium-dependent serotonin transporter (5HT transporter) (5HTT); solute carrier family 6 (neurotransmitter transporter serotonin) member 4 (5-hydroxytryptamine (serotonin) transporter); Solute carrier family 6 (neurotransmitter transporter serotonin) member 4 (5-hydroxytryptamine (serotonin) transporter); solute carrier family 6 (neurotransmitter transporter), member 4; solute carrier family 6 (neurotransmitter transporter, serotonin), member 4; solute carrier family 6 member 4; solute carrier family 6, member 4
• Gene Symbols: SLC6A4
• Host Species: Goat
• Immunogen: Synthetic peptide sequence (LHQGERETWGK) corresponding to the internal amino acids of SLC6A4 (aa 74-85).
• Purification Method: Ammonium sulfate precipitation
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 6532
• Target Species: Human
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG