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Invitrogen™ SLC6A8 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5110393

Catalog No. PIPA5110393


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Description

Description

Immunogen sequence: VVYYEPLVYN NTYVYPWWGE AMGWAFALSS MLCVPLHLLG CLLRAKGTMA ERWQHLTQPI WGLHHLEYRA QDADVRGLTT LTPVSESSKV VVVESVM.

SLC6A8 (solute carrier family 6 member 8), also known as CT1 (creatine transporter 1), CRT or CRTR, is a 635 amino acid multi-pass plasma membrane protein that belongs to the sodium/neurotransporter (SNF) family. Expressed in a variety of tissues including kidney, skeletal muscle, heart, brain, prostate, testis and colon, SLC6A8 functions to transport creatine into and out of cells, specifically those found in brain and muscle tissue. Creatine, an organic acid, occurs naturally and is essential for supplying the energy needed for proper muscle and nerve function. Defects in the gene encoding SLC6A8 lead to cerebral creatine deficiency and are the cause of X-linked creatine deficiency syndrome, a rare disorder characterized by facial anomalies, seizures and mental retardation. Multiple isoforms of SLC6A8 exist due to alternative splicing events.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

SLC6A8
Polyclonal
Unconjugated
SLC6A8
AA589632; CCDS1; choline transporter; CHOT1; CHT1; Creat; creatine transporter; creatine transporter 1; creatine transporter SLC6A8 variant D; creatine transporter, solute carrier family 6, member 8; CRT; CRTR; CT1; CTR5; MGC87396; Na+ dependent transporter; SLC6A8; Sodium- and chloride-dependent creatine transporter 1; solute carrier family 6 (neurotransmitter transporter), member 8; solute carrier family 6 (neurotransmitter transporter, creatine), member 8; solute carrier family 6 member 8; solute carrier family 6, member 8
Rabbit
Affinity chromatography
RUO
102857, 6535
-20°C, Avoid Freeze/Thaw Cycles
Liquid
ELISA, Western Blot
1.26 mg/mL
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
P48029, Q8VBW1
SLC6A8
Recombinant fusion protein containing a sequence corresponding to amino acids 539-635 of human SLC6A8 (NP_005620.1).
100 μL
Primary
Human, Mouse
Antibody
IgG
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