Invitrogen™ SLC7A5 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA533052

Catalog No. PIPA533052

Description

Percent identity with other species by BLAST analysis: Human, Gibbon (100%); Gorilla, Monkey (93%); Mouse, Rat, Dog, Bat, Panda (80%). For IHC(P), use heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.

Solute carrier family 7 member 5 also known as large neutral amino acids transporter small subunit 1 is a protein that in humans is encoded by the SLC7A5 gene.It is sodium-independent, high-affinity transport of large neutral amino acids such as phenylalanine, tyrosine, leucine, arginine and tryptophan, when associated with SLC3A2/4F2hc.It involved in cellular amino acid uptake and the transport of L-DOPA across the blood-brain barrier, and that of thyroid hormones triiodothyronine (T3) and thyroxine (T4) across the cell membrane in tissues such as placenta.Acts as an amino acid exchanger and plays a role in neuronal cell proliferation (neurogenesis) in brain.

Specifications

• Antigen: SLC7A5
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SLC7A5
• Gene Alias: 4F2; 4F2 LC; 4F2 light chain; 4F2HC; 4F2LC; 4T2HC; CD98; CD98 light chain; CD98HC; CD98LC; D0H16S474E; D16S469E; E16; hLAT1; integral membrane protein E16; large neutral amino acids transporter 1; large neutral amino acids transporter small subunit 1; LAT1; LAT-1; L-type amino acid transporter 1; MDU1; MP hLAT1; MPE16; NACAE; Protein TA1; SLC7A5; sodium-independent neutral amino acid transporter LAT1; solute carrier family 7 (amino acid transporter light chain, L system), member 5; solute carrier family 7 (cationic amino acid transporter, y+ system), member 5; solute carrier family 7 member 5; Ta1; tumor-associated protein 1; y+ system cationic amino acid transporter
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 8140
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 1 mg/mL
• Formulation: PBS with 0.1% sodium azide
• Gene Accession No.: Q01650
• Gene Symbols: SLC7A5
• Immunogen: Synthetic 15 amino acid peptide from internal region of human SLC7A5.
• Quantity: 50 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov