SLC7A5 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA565997

Catalog No. PIPA565997

Description

Immunogen sequence: DCINKYGSPYT KNSGFATCVQ NLPDQCTPNP CDRKGTQACQ DLMGNFFCLC KAGWGGRLCD KDVNECSQEN Highest antigen sequence identity to the following orthologs - mouse 76%, rat 82%.

CD98 light chain (CD98LC), also known as the 4F2 light chain, or LAT-1. CD98LC is a 40kD multi-pass membrane protein which forms a heterodimer with the CD98 heavy chain to allow transport of large branched chain, neutral amino acids into the cell. This transport system leads to the uptake of seven amino acids, including isoleucine, phenylalanine, and methionine. The expression levels of CD98LC are upregulated in a wide spectrum of primary human cancers. Changes in amino acid transporter expression are thought to be an early change in oncogenesis, as they impart growth and survival advantages.

Specifications

• Antigen: SLC7A5
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SLC7A5
• Gene Alias: SLC7A5; solute carrier family 7 (cationic amino acid transporter; y+ system); member 5; 4F2LC; CD98; D16S469E; E16; LAT1; MPE16; hLAT1; 4F2 light chain; CD98 light chain; L-type amino acid transporter 1; integral membrane protein E16; large neutral amino acids transporter 1; large neutral amino acids transporter small subunit 1; sodium-independent neutral amino acid transporter LAT1
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 8140
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunocytochemistry, Immunofluorescence, Western Blot
• Concentration: 0.05 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q01650
• Gene Symbols: SLC7A5
• Immunogen: Recombit Human SLC7A5
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

For Research Use Only