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Invitrogen™ SLC8A1 Polyclonal Antibody
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Catalog No. PIPA584833
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100 μL
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PIPA584833 100 μL
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Catalog No. PIPA584833 Supplier Invitrogen™ Supplier No. PA584833
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: RHAADQARKA VSMHEVNTEV TENDPVSKIF FEQGTYQCLE Highest antigen sequence indentity to the following orthologs: Rat - 90%, Mouse - 93%.

Ca2+ plays a critical role in intracellular signaling and thus regulation of calcium balance is critical for the maintenance of this signaling function. The plasma membrane Na+/Ca2+ (NaCX) exchangers mediate Na+-dependent Ca2+ efflux in a wide variety of cell types. NaCX can move Ca2+ either into or out of cells, depending on the net Na+, Ca2+, and K+ gradient across the membrane. In mammals, at least 5 distinct genes code for the exchangers: Three NaCX (NaCX-1, NaCX-2, and NaCX-3), and two in the NaCKX family (NaCKX-1 and NaCKX-2). NaCX-1 is most prominently expressed in the heart where it plays a major role in excitation-contraction coupling (Matsuoka et al., 1993). NACX-1 may also be a target for protection of the heart and brain from ischemia and reperfusion injury (Hagihara et al., 2005; Bano et al., 2005; Choi, 2005).
TRUSTED_SUSTAINABILITY

Specifications

Antigen SLC8A1
Applications Immunocytochemistry, Immunofluorescence
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Slc8a1
Gene Accession No. P32418
Gene Alias AI852629; AV344025; CNC; D930008O12Rik; Na(+)/Ca(2+)-exchange protein 1; Na/Ca exchanger; Na+/Ca++ exchanger; Na+/Ca2+ exchanger; Na-Ca exchanger; Ncx; Ncx1; Slc8a1; Sodium/calcium exchanger 1; sodium/calcium exchanger isoform NaCa7; solute carrier family 8 (sodium/calcium exchanger), member 1; solute carrier family 8 member 1; solute carrier family 8 member A1; solute carrier family 8, member 1
Gene Symbols Slc8a1
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human SLC8A1. Recombinant protein control fragment (Product #RP-107729).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6546
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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