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Invitrogen™ SLC8A2 Polyclonal Antibody
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Catalog No. PIPA562250
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100 μL
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PIPA562250 100 μL
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Catalog No. PIPA562250 Supplier Invitrogen™ Supplier No. PA562250
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: PANDSDTSTG GCQGSYRCQP GVLLPVWEPD DPSLGDKAA Highest antigen sequence identity to the following orthologs: Mouse - 85%, Rat - 95%.

Sodium/calcium exchanger proteins are integral membrane proteins primarily seen in cardiac cells. In cardiac myocytes, the concentration of Ca2+ alternates between low levels during relaxation and high levels during contraction. The Na+/Ca2+ exchanger 1 (NCX1) protein mediates Ca2+ extrusion from cardiac cells during relaxation. Four NCX1 isoforms (NCX1.1, NCX1.3, NCX1.7, and NCX1.10) result from alternate splicing. NCX1 mRNA is present at high levels in the heart, with lower levels present in the brain. NCX2 is most abundantly expressed in brain, in contrast the the broader distribution of NCX1, which is also expressed in heart, kidney, lung, smooth and skeletal muscle. The difference in expression for the transporter subtypes is believed to reflect differences in their functional roles. Regulation mechanisms for these exchanger proteins have not been fully characterized.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SLC8A2
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Slc8a2
Gene Accession No. Q9UPR5
Gene Alias KIAA1087; Na(+)/Ca(2+)-exchange protein 2; Na+/Ca2+-exchanging protein Nac2; NCX2; Slc8a2; sodium/calcium exchanger 2; sodium-calcium exchanger 2; solute carrier family 8 (sodium/calcium exchanger), member 2; solute carrier family 8 (sodium-calcium exchanger), member 2; solute carrier family 8 member 2; solute carrier family 8 member A2
Gene Symbols Slc8a2
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human SLC8A2. Recombinant protein control fragment (Product #RP-98990).
Purification Method Antigen Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6543
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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