Invitrogen™ SLCO4C1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5140093

Catalog No. PIPA5140093

Description

Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user. Immunogen sequence: PKHLPGTAEI QAGKTSQAHQ SNSNADVKFG KSIKDFPAAL KNLMK.

Organic anion transporter, capable of transporting pharmacological substances such as digoxin, ouabain, thyroxine, methotrexate and cAMP. May participate in the regulation of membrane transport of ouabain. Involved in the uptake of the dipeptidyl peptidase-4 inhibitor sitagliptin and hence may play a role in its transport into and out of renal proximal tubule cells. May be involved in the first step of the transport pathway of digoxin and various compounds into the urine in the kidney. May be involved in sperm maturation by enabling directed movement of organic anions and compounds within or between cells. This ion- transporting process is important to maintain the strict epididymal homeostasis necessary for sperm maturation. May have a role in secretory functions since seminal vesicle epithelial cells are assumed to secrete proteins involved in decapacitation by modifying surface proteins to facilitate the acquisition of the ability to fertilize the egg.

Specifications

• Antigen: SLCO4C1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SLCO4C1
• Gene Alias: 9530051F04; C330017E21Rik; Oatp4c1; OATP-H; OATP-M1; oatp-R; OATPX; Organic anion transporter M1; PRO2176; SLC21A20; SLCO4C1; solute carrier family 21 member 20; Solute carrier organic anion transporter family member 4C1; solute carrier organic anion transporter family, member 4C1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 353189
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunocytochemistry
• Concentration: 0.3 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q6ZQN7
• Gene Symbols: SLCO4C1
• Immunogen: Recombinant protein corresponding to Human SLCO4C1. Recombinant protein control fragment (Product #RP-108958).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG