Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. AB5701I

MilliporeSigma™ Slit2, Rabbit, Unlabeled, Polyclonal,

Catalog No. AB5701I Shop All MilliporeSigma Products
Change view
Click to view available options
Quantity:
100 μg
Conjugate:
Unconjugated
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity Conjugate
AB5701I 100 μg Unconjugated
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Catalog No. AB5701I Supplier MilliporeSigma™ Supplier No. AB5701I
Only null left
Add to Cart
Add to Cart

Description

Rabbit Polyclonal Antibody

Slit homolog 2 protein (UniProt O94813; also known as Slit-2, Slit2) is encoded by the SLIT2 (also known as SLIL3) gene (Gene ID 9353) in human. Slit proteins are essential for midline guidance in the forebrain where they act as repulsive signal preventing inappropriate midline crossing by axons projecting from the olfactory bulb. Slit-2 acts as molecular guidance cue in cellular migration and its function appears to be mediated by interaction with roundabout homolog receptors. During neural development it is involved in axonal navigation at the ventral midline of the neural tube and projection of axons to different regions. In the developing visual system it appears to function as repellent for retinal ganglion axons by providing a repulsion that directs these axons along their appropriate paths prior to, and after passage through, the optic chiasm. Ref.: Niclou, SP., et al. (2000) J Neurosci. 20; 4962-4974.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Slit2
Applications Western Blot
Classification Polyclonal
Concentration Please refer to lot specific datasheet.
Conjugate Unconjugated
Formulation Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene SLIT2, SLIL3
Gene Accession No. O94813
Host Species Rabbit
Immunogen KLH-conjugated linear peptide corresponding to a sequence within the CTCK domain of human Slit-2.
Purification Method Affinity Purified
Quantity 100 μg
Regulatory Status RUO
Research Discipline Neuroscience
Primary or Secondary Primary
Gene ID (Entrez) NP_004778
Test Specificity This polyclonal antibody targets region within the CTCK domain (a.a. 1453-1528) ane will therefore react with uncleaved Slit-2 and cleaved Slit-2 C-product (a.a. 1122-1529), but not the cleaved N-product (a.a. 31-1121).
Target Species Human
Content And Storage Stable for 1 year at 2°-8°C from date of receipt.
Show More Show Less

For Research Use Only. Not for use in diagnostic procedures.

Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.