SLIT2Rabbit anti-Chicken, Human, Polyclonal, Rockland™

Catalog No.	Quantity
50-194-3855	100 μg

Catalog No. 50-194-3855 Supplier Rockland Immunochemicals Supplier No. 600401846

Description

Rabbit Polyclonal Antibody

Store vial at -20°C prior to opening. Aliquot contents and freeze at -20°C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. This affinity purified antibody is directed against human SLIT-2 protein. A BLAST analysis was used to suggest reactivity with this protein from human and chicken based on 100% homology for the immunogen sequence. Expect cross reactivity with SLIT-2 from Tetraodon nigroviridis , as only a single amino acid residue change is found within the immunogen sequence (94% positive by BLAST). The core 13 amino acids of the immunogen are also 100% homologous to SLIT-2 from mouse, rat, bovine and Xenopus laevis. Cross reactivity with SLIT-2 homologues from other sources has not been determined.

SLIT2 are ligands for Robo receptors and play a vital role for axonal migration/navigation during neural development. A number of cleavage products through alternate splicing are reported in the literature for SLIT2 proteins. The C-terminal cleavage proteins are more diffusible than the larger N-terminal protein that is more tightly cell associated. SLIT2 protein is expressed in tissues such as fetal lung, kidney, and adult spinal cord.

Specifications

• Antigen: SLIT2
• Applications: ELISA, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
• Classification: Polyclonal
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: 0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
• Gene: SLIT2
• Gene Accession No.: O94813
• Gene Alias: downregulated during adipocyte differentiation-1; Drad-1; E030015M03Rik; E130320P19Rik; mKIAA4141; neurogenic extracellular slit protein; SLIL3; slit guidance ligand 2; slit homolog 2 (Drosophila); Slit homolog 2 protein; Slit homolog 2 protein C-product; Slit homolog 2 protein N-product; SLIT2; Slit-2
• Gene Symbols: SLIT2
• Host Species: Rabbit
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 373967, 9353
• Target Species: Chicken, Human
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid