Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

Invitrogen™ SLIT3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA544935

Catalog No. PIPA544935


Only null left
Add to Cart

Description

Description

Peptide sequence: PRRLANKRIS QIKSKKFRCS GSEDYRSRFS SECFMDLVCP EKCRCEGTIV Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 93%; Rabbit: 93%; Rat: 93%.

Slit guidance ligand 3 (SLIT3) is a gene located on chromosome 5q35.1, encoding a member of the SLIT family of proteins that play key roles in axon guidance and neuronal migration during development. SLIT3 functions as a secreted protein, influencing the directional growth and pathfinding of axons by interacting with its receptor, Robo, on the surface of neurons. This interaction is critical for establishing neural network architecture and maintaining proper neural connectivity. Beyond its role in the nervous system, SLIT3 is involved in processes such as angiogenesis and cell migration, impacting tissue development and repair. Dysregulation of SLIT3 expression or function has been associated with developmental abnormalities and various diseases, including cancer, where it may influence tumor cell invasion and metastasis. Research into SLIT3 continues to explore its therapeutic potential in modulating axon guidance and its implications in pathological conditions affecting both the nervous and vascular systems.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

SLIT3
Polyclonal
Unconjugated
SLIT3
b2b2362.1Clo; KIAA0814; Megf5; Multiple EGF-like domains protein 5; multiple epidermal growth factor-like domains 5; multiple epidermal growth factor-like domains protein 5; SLIL2; SLIL2FLJ10764; slit guidance ligand 3; slit homolog 3; slit homolog 3 (Drosophila); slit homolog 3 protein; SLIT1; slit2; SLIT3; Slit-3; UNQ691/PRO1336
Rabbit
Affinity chromatography
RUO
6586
-20°C, Avoid Freeze/Thaw Cycles
Liquid
Western Blot
0.5 mg/mL
PBS with 2% sucrose and 0.09% sodium azide
O75094
SLIT3
Synthetic peptide directed towards the N-terminal of human SLIT3 (aa 467-516).
100 μL
Primary
Human
Antibody
IgG
Product Suggestions

Product Suggestions

Videos
SDS
Documents

Documents

Product Certifications
Promotions

Promotions

Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Your feedback has been submitted: Thank you for helping us improve our website.