Invitrogen™ SLITRK4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA520481

Catalog No. PIPA520481

Description

A suggested positive control is mouse brain tissue lysate. PA5-20481 can be used with blocking peptide PEP-0601.

SLIT and NTRK-like family 4 (Slitrk4) is a member a protein family consisting of six homologous transmembrane proteins (Slitrk1-6) that share two conserved leucine-rich repeat domains in the extracellular domain and have significant homology to Slit, a secreted axonal growth-controlling protein. These proteins are also homologous to trk neurotrophin receptors in their intracellular domains. Expression of Slitrk proteins is highly restricted to neural and brain tumor tissues, but varies within the protein family. Like every other Slitrk protein except Slitrk1, overexpression of Slitrk4 inhibited neurite outgrowth in cultured neurons, suggesting that these proteins are involved in the control of neurite outgrowth.

Specifications

• Antigen: SLITRK4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SLITRK4
• Gene Alias: 6430513G13; D930039I09Rik; SLIT and NTRK like family member 4; SLIT and NTRK-like family, member 4; SLIT and NTRK-like protein 4; slit and trk like gene 4; Slitrk4
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 139065, 245446, 302473
• Content And Storage: 4°C
• Form: Liquid

• Applications: Immunohistochemistry, Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% sodium azide
• Gene Accession No.: Q810B8, Q8IW52
• Gene Symbols: SLITRK4
• Immunogen: A 13 amino acid peptide from near the carboxy terminus of human Slitrk4.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG