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Invitrogen™ SLITRK6 Polyclonal Antibody
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Catalog No. PIPA533055
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50 μg
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PIPA533055 50 μg
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Catalog No. PIPA533055 Supplier Invitrogen™ Supplier No. PA533055
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Description

Rabbit Polyclonal Antibody

Percent identity with other species by BLAST analysis: Human, Chimpanzee, Gibbon, Monkey, Rat, Hamster (100%); Gorilla, Galago, Marmoset, Mouse, Elephant, Pig (94%); Panda, Bovine, Bat, Dog, Horse, Zebra finch, Chicken (88%); Opossum, Turkey (81%). For IHC(P), use heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.

SLIT and NTRK-like family 6 (Slitrk6) is a member a protein family consisting of six homologous transmembrane proteins (Slitrk1-6) that share two conserved leucine-rich repeat domains in the extracellular domain and have significant homology to Slit, a secreted axonal growth-controlling protein. These proteins are also homologous to trk neurotrophin receptors in their intracellular domains. Expression of Slitrk proteins is highly restricted to neural and brain tumor tissues, but varies within the protein family. Slitrk6 expression has been observed in tissues such as tongue, lung, gastrointestinal tract, and pancreas. Like every other Slitrk protein except Slitrk1, overexpression of Slitrk6 inhibited neurite outgrowth in cultured neurons, suggesting that these proteins are involved in the control of neurite outgrowth. At least two isoforms of Slitrk6 are known to exisit.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SLITRK6
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.1% sodium azide
Gene SLITRK6
Gene Accession No. Q9H5Y7
Gene Alias 4832410J21Rik; DFNMYP; neuronal transmembrane protein Slitrk6; RP11-272M24.2; SLIT and NTRK like family member 6; SLIT and NTRK-like family, member 6; SLIT and NTRK-like protein 6; slit and trk like gene 6; SLITRK6; Sltk6
Gene Symbols SLITRK6
Host Species Rabbit
Immunogen Synthetic 16 amino acid peptide from internal region of human SLITRK6.
Purification Method Antigen affinity chromatography
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100765815, 290467, 84189
Target Species Human, Rat, Hamster
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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