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  5. Tocris Bioscience™ SLM 6031434 hydrochloride

Tocris Bioscience™ SLM 6031434 hydrochloride
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Catalog No. 628150
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Catalog No. Quantity
62-815-0 50 mg
62-811-0 10 mg
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Catalog No. 62-815-0 Supplier Tocris Bioscience™ Supplier No. 6281/50
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Description

Selective sphingosine kinase 2 (Sphk2) inhibitor

SLM 6031434 hydrochloride is a Sphk2 inhibitor (Ki = 0.4 μM for mouse Sphk2). Exhibits 40-fold selectivity for Sphk2 over Sphk1. Decreases levels of sphingosine-1-phosphate (S1P) in U937 cells in vitro and increases blood levels of S1P in wild-type mice .

Specifications

Chemical Name or Material (2S)-2-[3-[4-(Octyloxy)-3-(trifluoromethyl)phenyl]-1,2,4-oxadiazol-5-yl]-1-pyrrolidinecarboximidamide hydrochloride
CAS 1897379-34-8
Quantity 50 mg
Molecular Formula C22H30F3N5O2.HCl
Purity 98%
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