Invitrogen™ SLMAP Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5116713

Catalog No. PIPA5116713

Description

Positive Samples: HeLa, LO2 Immunogen sequence: IDTENLREEK DSEITSTRDE LLSARDEILL LHQAAAKVAS ERDTDIASLQ EELKKVRAEL ERWRKAASEY EKEITSLQNS FQLRCQQCED QQREEATRLQ GELEKLRKEW NALETECHSL KRENVLLSSE LQRQEKELHN SQKQSLELTS DLSILQMSRK ELENQVGSLK EQHLRDSADL KTLLSKAENQ AKDVQKEYEK TQTVLSELKL KFEMTEQEKQ SITDELKQCK NNLKLLREKG NNKPWPWMPM L.

Sarcolemmal membrane associated protein (SLMAP) is a tail-anchored membrane protein involved in the docking and membrane fusion process via protein-protein interactions. Deregulation of SLMAP expression plays an important role in type 2 diabetes, and changes in SLMAP expression are linked to hyperglycemia and diabetes. SLMAPs are components of cardiac membranes and have been identified as a novel regulator of cardiac function. There are several isoforms of SLMAPs with varying molecular size (35, 45, 63, and 83-91 kDa) as a result of alternative splicing. The short 35- kDa isoform is predominantly expressed in cardiac and slow-twitch skeletal muscle, while the 83- to 91- kDa isoform is ubiquitous.

Specifications

• Antigen: SLMAP
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Slmap
• Gene Alias: D330001L02Rik; KIAA1601; mKIAA1601; sarcolemma associated protein; sarcolemmal membrane-associated protein; Sarcolemmal-associated protein; Slap; Slmap; UNQ1847/PRO3577
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 290533, 7871, 83997
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 1.76 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: P0C219, Q14BN4, Q3URD3
• Gene Symbols: Slmap
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 540-790 of human SLMAP (NP_0090902).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov