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  5. Tocris Bioscience™ SM 324405

Tocris Bioscience™ SM 324405
GREENER_CHOICE

Catalog No. 544550
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Potent TLR7 agonist

SM 324405 is a potent TLR7 agonist (EC50 = 50 nM). Exhibits selectivity for TLR7 over TLR8. Induces IFN-α and -γ expression in human PBMCs and mouse splenocytes, and inhibits IL-5 production in human PBMCs in vitro. Rapidly metabolized to acid metabolite (t½ = 2.6 min in human plasma).

Specifications

Chemical Name or Material Methyl 3-[(6-amino-2-butoxy-7,8-dihydro-8-oxo-9H-purin-9-yl)methyl]benzeneacetate
CAS 677773-91-0
Quantity 50 mg
Target Toll-like Receptor Agonists
Molecular Formula C19H23N5O4
Formula Weight 385.42
Purity >98%
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