SMAD3Rabbit anti-Bovine, Chicken, Human, Mouse, Porcine, Rat, Xenopus laevis, Zebrafish, Polyclonal, Rockland™

Catalog No.	Quantity
50-199-1864	100 μg

Catalog No. 50-199-1864 Supplier Rockland Immunochemicals Supplier No. 600401920

Description

Rabbit Polyclonal Antibody

Store vial at -20°C prior to opening. Aliquot contents and freeze at -20°C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. SMAD3 affinity-purified antibody is directed against human Smad3 protein. A BLAST analysis was used to suggest reactivity with this protein from human, mouse, rat, swine, and chicken sources based on 100% homology for the immunogen sequence. ELISA and western blot show equivalent reactivity against phosphorylated and non-phosphorylated human SMAD3.

SMAD3 belongs to the SMAD family of proteins. They are similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor-beta and is thought to play a role in the regulation of carcinogenesis.

Specifications

• Antigen: SMAD3
• Applications: ELISA, Immunohistochemistry, Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 1.2 mg/mL
• Conjugate: Unconjugated
• Formulation: 0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
• Gene: Smad3
• Gene Accession No.: P84022, P84023, P84024, P84025, Q8BUN5
• Gene Alias: AU022421; BOS_10264; DKFZp586N0721; DKFZp686J10186; hMAD-3; hSMAD3; HSPC193; HsT17436; JV15-2; LDS1C; LDS3; MAD (mothers against decapentaplegic, Drosophila) homolog 3; MAD homolog 3; MAD homolog 3a; mad homolog JV15-2; mad protein homolog; MAD, mothers against decapentaplegic homolog 3; mad3; MAD-3; Madh3; madh3a; madh3-A; MGC60396; mMad3; Mothers against decapentaplegic homolog 3; mothers against DPP homolog 3; SMA- and MAD-related protein 3; SMAD; SMAD 3; SMAD family member 3; SMAD family member 3 L homeolog; SMAD family member 3a; SMAD, mothers against DPP homolog 3; Smad3; smad3.L; Smad3a; transcription factor; transcription factor Smad3; wu:fa99e03; XELAEV_18018454mg; XenMLP; Xmad3; XSmad3
• Gene Symbols: Smad3, smad3.L, smad3a
• Host Species: Rabbit
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 17127, 25631, 378633, 395132, 397260, 4088, 515125, 58092
• Target Species: Bovine, Chicken, Human, Mouse, Pig, Rat, X. laevis, Zebrafish
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid