Invitrogen™ SMAD5 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA589580

Catalog No. PIPA589580

Description

Immunogen sequence: STYPNSPASS GPGSPFQLPA DTPPPAYMPP DDQMGQDNSQ PMDTSNNMIP QIMPSISSRD VQPVAYEEPK HWCSIVYYEL NNRVGEAFHA SSTSVLVDGF T Positive Samples: SKOV3, MCF-7, Mouse kidney; Cellular Location: Cytoplasm, Nucleus.

SMADs are members of the MAD-related family of molecules. MAD-related proteins are a family of intracellular proteins that are essential components in the signaling pathways of the serine/threonine kinase receptors of the transforming growth factor beta superfamily. SMADs can be divided into receptor-regulated SMADs (R-SMADs: SMAD1, 2, 5, 8 and 9), common-mediator SMAD (co-SMAD: SMAD4), and inhibitory SMADs (I-SMADs: SMAD6 and 7). SMAD1, 5, 8 and 9 have high degrees of homology and antibodies are available that recognize sequences common to all of them. SMAD8 and SMAD9 are typically used as alternate names for one another in the literature.

Specifications

• Antigen: SMAD5
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SMAD5
• Gene Alias: 1110051M15Rik; AI451355; DKFZp781C1895; DKFZp781O1323; dwarfin-C; DWFC; Dwf-C; hSmad5; JV5-1; MAD homolog 5; MAD, mothers against decapentaplegic homolog 5; Madh5; Mothers against decapentaplegic homolog 5; mothers against decapentaplegic, drosophila, homolog of, 5; mothers against DPP homolog 5; mSmad5; MusMLP; OTTHUMP00000223331; SMA- and MAD-related protein 5; SMAD; SMAD 5; SMAD family member 5; SMAD, mothers against DPP homolog 5; SMAD5
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 17129, 4090, 59328
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.54 mg/mL
• Formulation: PBS with 50% glycerol and 0.09% sodium azide; pH 7.3
• Gene Accession No.: P97454, Q99717, Q9R1V3
• Gene Symbols: SMAD5
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 200-300 of human Smad5 (NP_0058943).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov