Invitrogen™ SMAD6 Monoclonal Antibody (5H3)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA515687

Catalog No. PIMA515687

Description

MA5-15687 targets SMAD6 in indirect ELISA, WB applications and shows reactivity with Human samples. The MA5-15687 immunogen is purified recombinant fragment of human SMAD6 expressed in E. Coli. . MA5-15687 detects SMAD6 which has a predicted molecular weight of approximately 53kDa.

SMAD6 (mothers against decapentaplegic homolog 6) is an antagonist of signaling by TGF-beta (transforming growth factor) type 1 receptor superfamily members; has been shown to inhibit selectively BMP (bone morphogenetic proteins) signaling by competing with the co-SMAD SMAD4 for receptor-activated SMAD1. SMAD6 is an inhibitory SMAD (I-SMAD) or antagonistic SMAD.

Specifications

• Antigen: SMAD6
• Classification: Monoclonal
• Concentration: Conc. Not Determined
• Formulation: ascites with 0.03% sodium azide
• Gene Accession No.: O43541
• Gene Symbols: SMAD6
• Immunogen: Purified recombinant fragment of human SMAD6 expressed in E. Coli.
• Regulatory Status: RUO
• Gene ID (Entrez): 4091
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: ELISA, Western Blot
• Clone: 5H3
• Conjugate: Unconjugated
• Gene: SMAD6
• Gene Alias: AOVD2; b2b390Clo; HsT17432; MAD homolog 6; mad homolog 7; Madh6; Madh7; Mothers against decapentaplegic homolog 6; mothers against decapentaplegic, drosophila, homolog of, 6; mothers against DPP homolog 6; Msmad6; SMAD; SMAD 6; SMAD family member 6; SMAD SMAD; SMAD, mothers against DPP homolog 6; SMAD6
• Host Species: Mouse
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1