Invitrogen™ SMAD6 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA599401

Catalog No. PIPA599401

Description

Antibody detects endogenous levels of total SMAD6.

SMAD6 (mothers against decapentaplegic homolog 6) is an antagonist of signaling by TGF-beta (transforming growth factor) type 1 receptor superfamily members; has been shown to inhibit selectively BMP (bone morphogenetic proteins) signaling by competing with the co-SMAD SMAD4 for receptor-activated SMAD1. SMAD6 is an inhibitory SMAD (I-SMAD) or antagonistic SMAD.

Specifications

• Antigen: SMAD6
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SMAD6
• Gene Alias: AOVD2; b2b390Clo; HsT17432; MAD homolog 6; mad homolog 7; Madh6; Madh7; Mothers against decapentaplegic homolog 6; mothers against decapentaplegic, drosophila, homolog of, 6; mothers against DPP homolog 6; Msmad6; SMAD; SMAD 6; SMAD family member 6; SMAD SMAD; SMAD, mothers against DPP homolog 6; SMAD6
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 17130, 4091
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: O35182, O43541
• Gene Symbols: SMAD6
• Immunogen: A synthesized peptide derived from human SMAD6(Accession O43541), corresponding to amino acid residues Q352-A402.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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