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Invitrogen™ SMAD7 Recombinant Rabbit Monoclonal Antibody (17H18L23)

Catalog No. 701940
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70-194-0 100 μg
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Catalog No. 70-194-0 Supplier Invitrogen™ Supplier No. 701940
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Description

Rabbit Recombinant Monoclonal Antibody

This antibody is predicted to react with Monkey, Rat, Mouse, Rabbit and Pig. Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

SMADs are members of the MAD-related family of molecules. MAD-related proteins are a family of intracellular proteins that are essential components in the signaling pathways of the serine/threonine kinase receptors of the transforming growth factor beta superfamily. SMADs can be divided into receptor-regulated SMADs (R-SMADs: SMAD1, SMAD2, SMAD5, SMAD8 and SMAD9), common-mediator SMAD (co-SMAD: SMAD4), and inhibitory SMADs (I-SMADs: SMAD6 and SMAD7). SMAD1, SMAD5, SMAD8 and SMAD9 have high degrees of homology and antibodies are available that recognize sequences common to all of them. SMAD8 and SMAD9 are typically used as alternate names for one another in the literature.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SMAD7
Applications Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone 17H18L23
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.2
Gene SMAD7
Gene Accession No. O15105
Gene Alias CRCS3; FLJ16482; hSMAD7; MAD (mothers against decapentaplegic, Drosophila) homolog 7; MAD homolog 7; MAD homolog 8; MADH7; MADH8; mothers against decapentaplegic homolog 7; Mothers against decapentaplegic homolog 8; Mothers against decapentaplegic, drosophila, homolog of, 7; mothers against decapentaplegic-like protein 7; mothers against DPP 7; mothers against DPP homolog 7; mothers against DPP homolog 8; SMAD; SMAD 7; SMAD family member 7; SMAD, mothers against DPP homolog 7; Smad7
Gene Symbols SMAD7
Host Species Rabbit
Immunogen Peptides corresponding to Human SMAD7 (aa 370-389, 343-355).
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4092
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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