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Invitrogen™ SMAD9 Monoclonal Antibody (3H2)
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Catalog No. PIMA519290
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100 μg
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Catalog No. Quantity
PIMA519290 100 μg
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Catalog No. PIMA519290 Supplier Invitrogen™ Supplier No. MA519290
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Description

Mouse Monoclonal Antibody

Peptide Sequence: MHSTTPISSL FSFTSPAVKR LLGWKQGDEE EKWAEKAVDS LVKKLKKKKG AMDELERALS CPGQPSKCVT IPRSLDGRLQ VSHCKGLPHV IYCRVWRWPD LQSHHELKPL ECCEFPFGSK QKEVCINPYH YRRVETPVLP PVLVPRHSEY NPQLSLLAKF RSASLHSEPL MPHNATYPDS FQQPPCSALP PSPSHAFSQS PCTASYPHSP GSPSEPESPY QHSDFRPVCY EEPQHWCSVA YYELNNRVGE TFQASSRSVL IDGFTDPSNN RNRFCLGLLS NVNRNSTIEN TRRHIGKGVH LYYVGGEVYA ECVSDSSIFV QSRNCNYQHG FHPATVCKIP SGCSLKVFNN QLFAQLLAQS VHHGFEVVYE LTKMCTIRMS FVKGWGAEYH RQDVTSTPCW IEIHLHGPLQ WLDKVLTQMG SPHNPISSVS.

SMADs are members of the MAD-related family of molecules. MAD-related proteins are a family of intracellular proteins that are essential components in the signaling pathways of the serine/threonine kinase receptors of the transforming growth factor beta superfamily. SMADs can be divided into receptor-regulated SMADs (R-SMADs: SMAD1, 2, 5, 8 and 9), common-mediator SMAD (co-SMAD: SMAD4), and inhibitory SMADs (I-SMADs: SMAD6 and 7). SMAD1, 5, 8 and 9 have high degrees of homology and antibodies are available that recognize sequences common to all of them. SMAD8 and SMAD9 are typically used as alternate names for one another in the literature. Mutations of this gene can lead to pulmonary hypertension, primary 2 (PPH2).
TRUSTED_SUSTAINABILITY

Specifications

Antigen SMAD9
Applications ELISA, Immunocytochemistry
Classification Monoclonal
Clone 3H2
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative; pH 7.4
Gene SMAD9
Gene Accession No. O15198
Gene Alias HGNC:6774; MAD; MAD homolog 9; MADH6; Madh8; MADH9; Mothers against decapentaplegic homolog 9; Mothers against decapentaplegic, drosophila, homolog of, 9; mothers against DPP homolog 9; PPH2; RP11-421P11.9; SMAD; SMAD 9; SMAD family member 9; SMAD, mothers against DPP homolog 9; SMAD8; SMAD8/9; SMAD8A; SMAD8B; SMAD9
Gene Symbols SMAD9
Host Species Mouse
Immunogen SMAD9 (AAH11559.1, 1 a.a. ~ 430 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification Method Affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4093
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG2a κ
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