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Invitrogen™ SMAD9 Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA129826
Description
PA1-29826 has been successfully used in Western blot applications, where a band of 51 kDa is detected. A549 cells can be used as a positive control for this antibody.
SMADs are members of the MAD-related family of molecules. MAD-related proteins are a family of intracellular proteins that are essential components in the signaling pathways of the serine/threonine kinase receptors of the transforming growth factor beta superfamily. SMADs can be divided into receptor-regulated SMADs (R-SMADs: SMAD1, 2, 5, 8 and 9), common-mediator SMAD (co-SMAD: SMAD4), and inhibitory SMADs (I-SMADs: SMAD6 and 7). SMAD1, 5, 8 and 9 have high degrees of homology and antibodies are available that recognize sequences common to all of them. SMAD8 and SMAD9 are typically used as alternate names for one another in the literature. Mutations of this gene can lead to pulmonary hypertension, primary 2 (PPH2).
Specifications
SMAD9 | |
Polyclonal | |
Unconjugated | |
SMAD9 | |
HGNC:6774; MAD; MAD homolog 9; MADH6; Madh8; MADH9; Mothers against decapentaplegic homolog 9; Mothers against decapentaplegic, drosophila, homolog of, 9; mothers against DPP homolog 9; PPH2; RP11-421P11.9; SMAD; SMAD 9; SMAD family member 9; SMAD, mothers against DPP homolog 9; SMAD8; SMAD8/9; SMAD8A; SMAD8B; SMAD9 | |
Rabbit | |
Protein G | |
RUO | |
4093 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Western Blot | |
0.5 mg/mL | |
PBS with 0.2% gelatin and 0.05% sodium azide | |
O15198 | |
SMAD9 | |
Synthetic peptides corresponding to amino acids 22-36 and 317-331 of human SMAD8. | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG |
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