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Invitrogen™ SMAGP Polyclonal Antibody
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Catalog No. PIPA547555
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100 μg
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PIPA547555 100 μg
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Catalog No. PIPA547555 Supplier Invitrogen™ Supplier No. PA547555
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Description

Goat Polyclonal Antibody

In direct ELISAs and Western blots, approximately 40% cross-reactivity with recombinant human SMAGP is observed. Reconstitute at 0.2 mg/mL in sterile PBS.

Small cell adhesion glycoprotein (SMAGP) is a gene located on chromosome 1p33 that encodes a transmembrane protein involved in cell adhesion processes. SMAGP is primarily expressed in epithelial tissues and plays a role in maintaining cellular architecture and tissue integrity. This glycoprotein contributes to the organization of cell-cell junctions, which are critical for epithelial barrier function and communication between cells. Altered expression of SMAGP has been observed in various cancers, including gastric and colorectal cancers, where it may influence tumor progression and metastasis by affecting cellular adhesion and epithelial-to-mesenchymal transition (EMT). Research into SMAGP continues to explore its functional mechanisms in epithelial biology and its potential as a biomarker for cancer diagnosis and prognosis. By providing insights into the molecular pathways governing cell adhesion and tumorigenesis, studies on SMAGP contribute to the broader understanding of cancer biology and therapeutic opportunities.
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Specifications

Antigen SMAGP
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 5% trehalose and No Preservative
Gene SMAGP
Gene Accession No. Q7TPF1
Gene Alias hSMAGP; Smagp; Small cell adhesion glycoprotein; small cell transmembrane and glycosylated protein; small transmembrane and glycosylated protein; small trans-membrane and glycosylated protein
Gene Symbols SMAGP
Host Species Goat
Immunogen E. coli-derived recombinant rat SMAGP Met1-Thr34, Phe56-Ile97.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 300236
Target Species Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Lyophilized
Isotype IgG
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